xRead - Olfactory Disorders (September 2023)
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PATEL et al.
TABLE VII.17 (Continued) Author Year
Design LOE Study groups
Olfactory indicator Smoking measure Conclusions
Smoking-mediated OD is reversible but may persist for 15 years after smoking cessation Former smokers who had quit within 15 years had significantly impaired olfaction compared with never-smokers, but those who quit > 15 years ago had similar olfaction as never-smokers Current smoking (vs never-smoking) was
SS-ID (5 odors)
Nonsmokers, former smokers (asking age started smoking regularly, age quit, number of cigarettes smoked on average per day), and current smokers (age started, number of
4
3528 older adults, including 1526 former smokers
Siegel
2019
Population survey, case series
et al. 987
cigarettes on average day)
Schubert et al 988
2015
Prospective cohort
2
3296 participants (aged 21–84 years) in the
SDOIT
Current, former, or never-smoker
associated with increased risk of olfactory decline
baseline Beaver Dam Offspring Study (2005–2008), and 2792 (84.7%) of them, plus an additional 80 individuals who were unable to participate in the baseline phase participants aged ≥ 40 years, 1281 (70.5%) completed the examination
PST
Current, ever, and never-smoker
Smoking was not
Hoffman et al 989
4
1818 NHANES
2016
US
identified as a risk factor for OD; the logistic regression unexpectedly showed that past smoking, after adjusting for age and sex, was associated with decreased risk of OD Smoking did not explain the worse OF found in Black and Hispanic participants, who had markedly worse OF (controlling for sex and age) compared withWhite participants In re-analysis of these data (Ajmani et al,
nationally represen tative, cross sectional
Pinto
2014
Cross
4
n = 3005,with oversampled Blackand Hispanic individuals,
SS-ID (5 odors)
Current smoking,
et al. 528
sectional survey
based on either salivary cotinine level (n = 2219) or self-report (n = 709)
men, and oldest participants
2017, see below), smoking did not
associate significantly with the odds of OD
(Continues)
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