xRead - Olfactory Disorders (September 2023)

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491

PATEL et al.

TABLE VIII.3 (Continued) Study

Year LOE Study design

Study groups

Clinical end point OFCCCRCID MRI: OB morphology, brain lesions SPECT: brain perfusion SS-TDI Chemosensory ERPs OBV

Conclusions

Posttraumatic anosmics exhibited damage to the frontal lobes and OB

Altighechi et al 1062

2009 3

Prospective cohort

21 patients with PTOD 19 patients without PTOD 63 normosmic controls 10 patients with PIOD 5 patients with PTOD 9 patients with IOD

Goektas

2009 3

Prospective cohort

Association between OBV and presence of olfactory ERPs No correlation between OBV and TDI score OBV changes correlated with odor threshold changes OBs were smaller in patients with OD compared with controls OBV correlated with OF OBs were smaller in patients with parosmia Patients with congenital anosmia had aplastic or hypoplastic OB OS depth reflected the presence of olfactory tract OB abnormalities were seen (hypoplastic, 43%; signal abnormalities, 91.3%) POC showed signal abnormalities in 21% cases prognosis factor for olfactory recovery OF was significantly associated with the OB integrity was a overall MRI score, but not with the OBV or OS length significantly higher in patients with anosmia/hyposmia vs those with normosmia signal between groups (Continues) OB atrophy was No difference in OB

et al 1063

Haehner

2008 3

Prospective

20 patients with olfactory loss

SS-TDI at baseline and follow-up OBV at baseline and follow-up

et al 1064

before-after trial

Mueller

2005 3

Prospective cohort study

22 patients with PIOD 9 patients with PTOD 17 normosmic controls 16 patients with congenital anosmia 8 normosmic controls 23 patients with persistent COVID-19– related OD

SS-TDI OBV

et al 253

Abolmaali et al 917

Assessment of frontobasal structures

2002 3

Prospective cohort

Kandemirli et al 1054

2020 4

Case series

SS-TDI OBV and quality and OSdepth CTof theOC

AbdelBari et al 1065

2020 4

Retrospective

70 patients with PTOD

OB integrity OFSS-TDI

Langdon et al 1066

2018 4*

Prospective

42 patients with

OF (VAS, BAST-24, n-butanol thresholds) MRI traumatic lesion score

randomized controlled

traumatic brain injury–induced OD

Chung

2018 4

Retrospective case series

34 patients with OD

Korean SS-TDI Questionnaires

et al 255

(SNOT-22, QOD)

OBV and signal