xRead - Olfactory Disorders (September 2023)

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INTERNATIONAL CONSENSUS ON OLFACTION

TABLE IX-24 (Continued) Study

Year LOE Disease

Study design Study groups

Clinical end point Conclusions

UPSIT R

Kopala

1995

3

AN

Cohort

77 participants (n = 27 patients with AN)

UPSIT R scores

et al 954

normal for patients withAN metabolic or nutritional disturbances are unlikely tobe responsible for long-term OD OF decreases in IDA patients IDA is cause of desideros mia that is an olfactory craving phe nomenon and this phe nomenon is treated with IDA treatment: iron present in patients with vitamin B12 deficiency (vitamin B1) and folate in the diet 2 to 8 years prior inPD patients related with ODat the timeof PD diagnosis vitaminB treatment is not effective after 2 months, but if vitamin B given for full 6months, ODmaybe Low thiamin Systemic Transient

Dinc

2016 3

IDA

Cohort

100 participants (n = 50 IDA patients)

SS-TDI

et al 1511

Hansen

2017

4

IDA

Case series

3 patients with IDA Olfactory craving symptoms (self-reporting)

et al 1512

Derin

2016 2

Vitamin B12 deficiency

Double-blind

73 patients (n = 39 patients with low level vitamin B12)

SS-TDI

et al 1289

randomized, placebo controlled clinical

Håglin

2016 3

Vitamin B intake, PD Cohort

420 participants (n = 84 cases, PD)

B-SIT

et al 1513

Heilmann et al 1514

2004 3

Posttraumatic,

Cohort

192 patients (n = 72 cases,

SS-TDI

postinfectious olfactory loss, vitamin B and corticosteroid treatment

postinfectious olfactory loss)

(Continues)