xRead - Olfactory Disorders (September 2023)

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PATEL et al.

TABLE VII.6 Section evidence summary: Related to head trauma Study Year LOE Study design

Study groups

Clinical end point Subjective smell loss + PST

Conclusions

In responders aged ≥ 40 years, 10.1% of those with head injury and LOC had smell loss and 10.0% of those with facial or skull base injury had smell loss Head trauma was the etiology of smell loss in 12% of patients with OD impairment occured in 23.6% and 26.6% of Olfactory occupationally head-injured workers had smell impairment This was associated with LOC, more severe injuries, and skull fracture 19.7% of patients with TBI had olfactory impairment This was associated 7.5% of all head injury patients experienced olfactory impairment 39% experienced some recovery 17% of patient with olfactory loss had traumaas a etiology motor vehicle accidents and domestic falls, respectively 13.7%of with increased severity of TBI and comorbid medical illnesses

Responders reporting head injury with LOC(n = 178) Responders reporting serious injury to the face and/or skull (n = 203)

Hoffman et al 122

2016

4

Cross-sectional

national health survey

Schreiver et al 299

2020

4

Case series

Pediatric patients

SS-TDI

seen in a smell and taste clinic (n = 164)

Costanzo et al 300

1986

4

Case series

Patients with head trauma

Not specified

Ogawa

1999

4

Cross-sectional survey

Occupationally head-injured

Psychophysical smell testing

et al 301

workers (n = 365)

Singh

2018

4

Case series

Patients with TBI (n = 774)

OF assessed via

et al 302

sensitivity to coffee granules

Sumner 303

1964

4

Case series

Patients presenting

Subjective smell loss

with a wide variety of head injuries, from minor to more severe (n = 1167)

Temmel et al 69

SS-TDI

2002

4

Case series

Patients with anosmia or hyposmia (n = 278)

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