xRead - September 2022

Wise et al.

Page 362

Author Manuscript Author Manuscript Author Manuscript Author Manuscript TABLE IX.B.1.a-2. Dosage Drug

Elimination (hours) Adults Children

Cetirizine 0.7 <24 Unlikely 6.5–10 5–10 mg QD 2–5 years; 2.5 mg or 5 mg QD; 6–12 years: 5–10 mg QD Desloratadine 2–2.6 >24 Unlikely 27 5 mg QD 2–5 years: 1.25 mg QD; 6–11 years: 2.5 mg QD

Bilastine 2 24 Unlikely 14.5 20 mg QD 6–11 years: 10 mg QD Fexofenadine 1–3 >24 Unlikely 11–15 60 mg BID or 180 mg QD 2–11 years: 30 mg BID Levocetirizine 0.7 >24 Unlikely 7 5 mg QD 2–5 years: 1.25 mg QD; 6–11 years: 2.5 mg QD; ≥12 years: 2.5–5 mg QD ≥6 years; 10 mg QD

Loratadine 2 >24 Unlikely 7.8 10 mg QD or5mg BID 2–5 years; 5 mg QD;

interactions

Duration (hours)

medication Onset (hours)

Antihistamine

BID = twice per day; N/A = not applicable; QD = once per day.

List of commonly used second-generation antihistamines

Int Forum Allergy Rhinol . Author manuscript; available in PMC 2020 June 10.