xRead - Nasal Obstruction (September 2024) Full Articles

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ICAR SINONASAL TUMORS

TABLE XIV.1 (Continued)

Clinical endpoints

Study

Year LOE Study design Study groups

Conclusion

Sunet al. 396

1. 5-year OS 2. 5-year LRFFS

1. OS70% 2. LRFFS 78% 3. Orbital invasion, intracranial invasion, lymph node metastasis, and advanced Kadish disease at initial diagnosis were significantly associated with inferior prognosis 1. LC66% 2. DFS58% 3. OS62% 4. Orbital content retention rate in preoperative RT group was 85.7%, superior to 58.3% in postoperative RT group 1. LC 85%/65% 2. 81%/63% 3. Reduction of acute and late ocular toxicity of grade ≥ 2with VMAT 1. OS64% 2. OS71% 3. 5-year LRRFS survival was 100% in patients with ENI and 58% in patients without ENI Neoadjuvant RT was associated with an 81% decreased odds of positive margins There was no significant difference between the ENI ( + ) andENI ( − ) groups regarding OS and PFS 1. LRC88% 2. OS92%

2020 4

Retrospective case series

ONB at a single

institution (IMRT n = 71, 60 conven tional/3DCRT)

Wanget al. 492

2020 4

Retrospective case series

SNM at a single

1. 5-year LC 2. 5-year DFS 3. 5-year OS

institution ( n = 140; IMRT n = 84, 2D/3DCRT = 56)

Frederic

1. 3-year LC

2019 4

Retrospective case series

SNM at a single

Moreau et al. 493

VMAT/3DCRT

institution (IMRT n = 34, 3DCRT = 24)

2. 3-year OS

MVAT/3DCRT

Guazzo et al. 494

2019 4

Retrospective case series

ACC at a single

1. 5-year LRC 2. 5-year OS

institution (SNM n = 17)

Li et al. 495

1. 5-year OS RT alone 2. 5-year OS postopRT Margin status neoadjuvant versus adjuvant RT ENI impact on OSandPFS 1. 3-year RFS 2. 3-year OS 1. 5-year PFS 2. 5-year OS 1. 5-year LRC 2. 5-year OS

2019 4

Retrospective case series

ONB at a single

institution ( n = 88; IMRT n = 26, 3DCRT n = 34)

Fuet al. 380

2018 4

Retrospective case series

SNM at a single

institution ( n = 84)

Lee et al. 496

2018 4

Retrospective case series

SNM at a single

institution ( n = 40; IMRT n = 35, 3DCRT n = 5)

de Bonnecaze et al. 497 Chopra et al. 498

2018 4

Retrospective case series Retrospective case series Retrospective case series

SNUC at a single

1. RFS48% 2. OS62% 1. PFS30% 2. OS60% 1. LRC71% 2. OS44%

institution ( n = 54)

2017 4

SNM at a single

institution ( n = 23)

Gamez et al. 499

2017 4

SNUC at a single institution

(IMRT = 24, 3DCRT = 12, other = 4)

3. Better outcomes were obtained with a trimodality approach and doses 3 60Gy Patients with STR and rapid onset of MRI changes in post-surveillance scans are more likely to have tumor recurrence versus radiation necrosis (Continues)

Ahmad et al. 500

2016 4

Retrospective case series

SNM at a single

Intracranial radiation necrosis

institution ( n = 26)

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