xRead - Nasal Obstruction (September 2024) Full Articles

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KUANetal.

TABLE XIX.B.1 (Continued)

Clinical endpoints

Study

Year LOE Study design Study groups

Conclusions

Histopathologic features

OP may demonstrate on pathology B-cell clonality without meeting pathologic or clinical criteria for IgG4-ROD On MRI, tumor blood flow and apparent diffusion-coefficient alone and in combination may differentiate OP from orbital lymphoma

Derakhshandeh et al. 952

2021 4

Retrospective case series

Cases of inflammatory pseudotumor ( n = 13) OP ( n = 21) and orbital lymphoma patients ( n = 16)with MRI-specific findings of tumor blood flow, arterial-spin labeling, apparent diffusion coefficient, and diffusion-weighted imaging Pathology-confirmed OP ( n = 28) and ocular adnexal lymphoma patients ( n = 28) retrospectively divided into training ( n = 42) and testing groups ( n = 14) IgG4-ROD patients with ocular adnexal lesions ( n = 82) diagnosed with OP with presenting radiology and 12-month clinical follow-up ( n = 89) steroid-dependent or resistant IgG4-ROD treated with rituximab ( n = 5) Histopathologically confirmed cases of IgG4-ROD( n = 65) Biopsy-confirmed cases of Patients clinically

Eissa et al. 954

2021 4

Retrospective cohort

1. AUC 2. Sensitivity 3. Specificity

4. PPV 5. NPV

Houet al. 953

OP and ocular adnexal lymphoma may be differentiated on MRI using machine-learning enhanced algorithms

1. AUC 2. Sensitivity 3. Specificity

2021 4

Retrospective cohort

4. PPV 5. NPV

Kubota et al. 961

2020 4

Retrospective case series

Long-term

CN V and/or extraocular muscle involvement may confer long-term disease refractoriness to systemic corticosteroid treatment Patients diagnosed with OP that have infra-orbital nerve enlargement have higher recurrence following corticosteroid treatment Rituximab resulted in clinical and radiologic improvement with relatively benign side effect profile in patients with IgG4-ROD that is steroid dependent or steroid-resistant 1. Lacrimal gland enlargement was the most frequently observed lesion (87.7%) 2. 31 patients (47.7%) had lacrimal gland involvement alone

recurrence

Lee et al. 955

1. Clinical features 2. Radiographic findings

2016 4

Retrospective case series

Wuet al. 959

2015 4

Retrospective case series

1. Adverse events 2. Treatment outcomes

Sogabe et al. 949

1. Clinical features 2. Lesion

2014 4

Retrospective case series

frequency

3. Lesion

location

(Continues)