xRead - Nasal Obstruction (September 2024) Full Articles

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478

International consensus statement on rhinosinusitis

(Continues)

Decreased

Increased

Increased

Increased

Innate Immunity Activity Increased

Increased

Increased

Increased

Increased

RT-PCR FACS Tissue IL-25 IL-25 mRNA level was significantly lower in the CRSwNP group compared to the control.

H&E staining IHC Tissue IL-33 IL-33 protein level was significantly higher in the CRSwNP group compared to the control.

RT-PCR IHC Tissue IL-33 IL-33 expression levels in the CRSwNP group were significantly higher than those in the control group, especially in the ECRSwNP group. ELISA IHC PCR

Tissue IL-33 IL-33 was highly expressed in the polyps of ECRS patients.

Tissue IL-25 IL-25 mRNA level was significantly higher in the CRSwNP group compared to the control.

Tissue IL-33 The mRNA level, but not protein levels of IL-33 were significantly elevated in polyp tissues as

compared to the control uncinate.

RT-PCR IHC Tissue IL-33 IL-33 protein level was significantly higher in the CRSwNP group compared to the control.

RT-PCR Tissue IL-25 The mRNA level of IL-25 were significantly elevated in polyp tissues as compared to the control.

Sinoasal tissue Nasal polyps ELISA Tissue IL-33 IL-33 mRNA levels was significantly higher in the CRSwNP group compared to the control. Sinoasal tissue Nasal polyps Nasal tissue Nasal polyps RT-PCR IHC

Type of Innate Immunity Findings

Study Groups (size) Tissue Technique IHC

RT-PCR

ELISA

Sinoasal tissue Nasal polyps

Sinoasal tissue Nasal polyps

Sinoasal tissue Nasal polyps

Sinoasal tissue Nasal polyps

Nasal tissue

Nasal polyps

Sinoasal tissue Nasal polyps

Lam 831 2012 CRSsNP (18)

Dogan 1498 2019 CRSwNP (33)

Shin 830 2015 CRSsNP (65)

Kim 832 2016 CRSsNP (61)

Hong 162 2018 CRSsNP (20)

Miljkovic 1501 2014 CRSsNP (13)

CRSwNP (7)

Control (32)

Nagata 1461 2019 ECRS (22)

Non-ECRS (11) Control (6)

Song 1502 2017 ECRSwNP (25)

nECRSwNP (27) Control (12)

Kouzaki 1503 2016 ECRS(17)

Control (10)

CRSwNP (50)

Control (27)

CRSwNP (12) Control (7)

Control (29)

CRSwNP (90) Control (16)

CRSwNP (166) Control (19)

TABLE X-13 (Continued) Study Year

IL-33