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International consensus statement on rhinosinusitis

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953. Gabra N, Alromaih S, Endam LM, et al. Clinical features of cytotoxic CD8 + T-lymphocyte deficiency in chronic rhi nosinusitis patients: a demographic and functional study. Int Forum Allergy Rhinol . 2014;4(6):495-501. 954. Khalid AN, Mace JC, Smith TL. Outcomes of sinus surgery in ambulatory patients with immune dysfunction. AmJ Rhinol Allergy . 2010;24(3):230-233. 955. May A, Zielen S, von Ilberg C, Weber A. Immunoglobulin defi ciency and determination of pneumococcal antibody titers in patients with therapy-refractory recurrent rhinosinusitis. Eur Arch Otorhinolaryngol . 1999;256(9):445-449. 956. Williams P, White A, Wilson JA, Yap PL. Penetration of administered IgG into the maxillary sinus and long-term clin ical effects of intravenous immunoglobulin replacement ther apy on sinusitis in primary hypogammaglobulinaemia. Acta Otolaryngol . 1991;111(3):550-555. 957. Collins FS, Morgan M, Patrinos A. The human genome project: lessons from large-scale biology. Science . 2003;300(5617):286-290. 958. Cormier C, Mfuna Endam L, Filali-Mouhim A, et al. A pooling-based genomewide association study identifies genetic variants associated with Staphylococcus aureus colo nization in chronic rhinosinusitis patients. Int Forum Allergy Rhinol . 2014;4(3):207-215. 959. Zariwala MA, Knowles MR, Leigh MW. Primary ciliary dysk inesia. In: Adam MP, Ardinger HH, Pagon RA, et al., eds. GeneReviews( R ) . Seattle (WA): University of Washington, Seattle Copyright © 1993-2020, University of Washington, Seattle. GeneReviews is a registered trademark of the Univer sity of Washington, Seattle. All rights reserved.; 1993. 960. Oakley GM, Curtin K, Orb Q, Schaefer C, Orlandi RR, Alt JA. Familial risk of chronic rhinosinusitis with and without nasal polyposis: genetics or environment. Int Forum Allergy Rhinol . 2015;5(4):276-282. 961. Bohman A, Oscarsson M, Holmberg K, et al. Heredity of nasal polyps. Rhinology . 2015;53(1):25-28. 962. Valera FCP, Ruffin M, Adam D, et al. Staphylococcus aureus impairs sinonasal epithelial repair: effects in patients with chronic rhinosinusitis with nasal polyps and control subjects. J Allergy Clin Immunol . 2019;143(2):591-603.e593. 963. Purnell PR, Addicks BL, Zalzal HG, et al. Single nucleotide polymorphisms in chemosensory pathway genes GNB3, TAS2R19, and TAS2R38 are associated with chronic rhinosi nusitis. Int Arch Allergy Immunol . 2019;180(1):72-78. 964. Mfuna Endam L, Filali-Mouhim A, Boisvert P, Boulet LP, Bosse Y, Desrosiers M. Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study. Int Forum Allergy Rhinol . 2014;4(3):200-206. 965. Weinhold B. Epigenetics: the science of change. Environ Health Perspect . 2006;114(3):A160-A167. 966. Kim JY, Kim DK, Yu MS, Cha MJ, Yu SL, Kang J. Role of epige netics in the pathogenesis of chronic rhinosinusitis with nasal polyps. MolMedRep . 2018;17(1):1219-1227. 967. Kidoguchi M, Noguchi E, Nakamura T, et al. DNA methyla tion of proximal PLAT promoter in chronic rhinosinusitis with nasal polyps. Am J Rhinol Allergy . 2018;32(5):374-379. 968. Seiberling KA, Church CA, Herring JL, Sowers LC. Epigenet ics of chronic rhinosinusitis and the role of the eosinophil. Int Forum Allergy Rhinol . 2012;2(1):80-84.