xRead - Olfactory Disorders (September 2023)

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480

INTERNATIONAL CONSENSUS ON OLFACTION

TABLE VII.17 (Continued) Author Year

Design LOE Study groups

Olfactory indicator Smoking measure Conclusions

SIT

Smoking: yes/no Smokers had lower OF preoperatively and postoperatively

2b

60 patients

Erdem

2019

Prospective, preopera

et al 1010

post-CABG (first time) divided into 30 off-pump and 30 on-pump CABG groups 323 patients with PDand323 controls closely matched individually on age, sex, and smoking history (never, past, or current) relatives (aged > 50years, within 10 years of the age of PD onset), free of conditions that could affect OF; excluded current smokers 173 first-degree 418 patients with preoperative olfactory data by ECRS or NECRS with a diagnosis of CRS recruited fromthree tertiary care centers over a 3-year period men, 7 women; mean age, 43 years)who underwent functional ESS smokers; 18 had undergone previous surgical intervention for their nasal disease 37 patients (30 13 (35.1 %) were cigarette 396 participants

tiveand postoper ative study

Sharer

2015

Case

4

UPSIT R

Never-, past, current smoker

In controls, smokers had significantly lower odor idenitification scores; current PD smokers had higher odor identification scores than former or never-smokers

et al 1011

control analysis

Siderowf et al 1012

UPSIT R

Nonsignificant

2007

Observational 4

Never smokers (1 to 10 lifetime

association between former smoking status

pack-years) and > 10 pack-years

and olfactory performance

Mori

2013

Multicenter prospec tive cohort study Multiinsti tutional cross sectional analysis

2b

T&T olfactometer and intravenous olfactory test (garlic odor)

Past, current,

Current smoking was a risk factor for ECRS OD was more severe and more prevalent in patients with ECRS than in patients with NECRS

et al 145

nonsmokers

Litvack

UPSIT R

2b

2008

Current tobacco use Current smokers were at increased odds of anosmia as compared with patients < 65 years, without nasal polyposis, nonasthmatics, and nonsmokers

et al 1013

Sugiyama et al 1014

2002

Case series 4

UPSIT R

Pack-years

Significant correlation between greater pack-years and lower postoperative OF in a population with high levels of smoking

(Continues)