xRead - Olfactory Disorders (September 2023)

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391

PATEL et al.

TABLE VII.9 (Continued) Disease Study

Year LOE Study design Study groups

Clinical end point Conclusions

SLE

Cavaco

2012 4

Case-control

85 patients with SLE and 85 controls

B-SIT

Patients with SLE and neuropsychiatric SLE scored worse on B-SIT compared with controls Greater OD in patients with neuropsychiatric SLE than controls or nonneuropsychiatric SLE patients OD was correlated with SLE disease activity OD was seen in 54.5% of patients with SLE, 59.3% of patients with SSc, and 14.45% ofHCs OD was associated with age, inflammation, and smaller hippocampi and amygdalae volumes In patients with SLE, OD was associated with anti-P antibodies and and presence of anti-P antibodies

et al 437

Chen

2019 4

Case-control

65 patients with SLE and 50 controls

CCCRC olfactory test

et al 438

Bombini et al 403

SS-TDI, MoCA, BAI, BDI, MRI, (anti-P) antibodies

2018 4

Longitudinal

143 patients with SLE, 57 patients with SSc, and 166 HCs

case-control

anxiety and depression symptoms

Shoenfeld et al 439

2009 4

Case-control

50 patients with SLE and 50 controls

SS-TDI

Patients with SLE

scored worse on TDI than controls

Rheumatoid arthritis

Steinbach et al 440

2011

4

Cross-sectional, case-control

111 patients

SS-TDI

Patients with

rheumatoid arthritis scored worse on overall TDI and threshold compared with controls

No correlation with disease activity, severity, extra-articular manifestations, or autoantibodies myasthenia gravis UPSIT R < HCs polymiositis UPSIT R < HCs Patients with Patients with

Myasthenia gravis

Leon

2012 4

Cross-sectional, case-control

27 patients with

UPSIT R

Sarmiento et al 441

myasthenia gravis, 11 patients with polymiositis,and 27 HCs

(Continues)