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Wise et al.

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Author Manuscript Author Manuscript Author Manuscript Author Manuscript Top SNPs for AR p Nearby gene(s) Reported association with other allergic diseases Protein function LOE Eczema, 487, 490 asthma, atopy 487

rs10197862 2E–09 IL1RL1 Asthma 487, 514 ; eczema 487 ; atopy 487 Proinflammatory effects, T helper cell function

Author (year) Study design Sample size Ethnicity

AA = African American; AR = allergic rhinitis; EA = European ancestry; GWAS = genome-wide association study; L = Latino; LOE = level of evidence; NADPH = nicotinamide adenine dinucleotide phosphate.

Int Forum Allergy Rhinol . Author manuscript; available in PMC 2020 June 10.